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Welcome to our website on teratoma. Our aim is to provide you with information on how cells fail to migrate to stem cell niches during development and how this results in disease.

 What is a teratoma?

Teratomas belong to a class of tumours known as NSGCT and they can be either benign or malignant. It is a neoplasm of multiple tissue types, developed from pluripotent germ cells, which are foreign to the site of where they should normally develop. It is not abnormal for teratomas to contain clusters of hair, teeth, bone and very rarely complex organs such as eyes and limbs. The tumour can either be solid or carry fluid within it. The tumour is made up of different types of tissue from one or more of the germ layers.  These tumours are mainly found in gonads, rarely some are found in the head and neck which come from Rathke’s pouch remnants of sphenoid bone region, lateral neck, tongue. Teratomas formed in Rathke’s pouch can extend into the oral cavity. The discovery of the tumour varies between the forms of teratomas ranging from prenatal and postnatal establishment. Generally teratomas are congenital in the case where they are small, they do not discovered until laters years of life.

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